Molecularly Imprinted Resins for Chiral Separation of Amino Acids
نویسندگان
چکیده
منابع مشابه
Molecularly Imprinted Polymers for the Identification and Separation of Chiral Drugs and Biomolecules
Molecularly imprinting polymers (MIPs) have been extensively applied in chromatography for the separation of chiral drugs. In this review, we mainly summarize recent developments of various MIPs used as chiral stationary phases (CSPs) in high performance liquid chromatography (HPLC), capillary electrochromatography (CEC), and supercritical fluid chromatography (SFC). Among them, HPLC has the ad...
متن کاملMolecularly Imprinted Polymers for the Enantioseparation of Methylephedrine Chiral Drug
In this study molecular imprinting technology was employed to prepare a specific affinity sorbent for the resolution of Methylephedrine, a chiral drug. The molecularly imprinted polymer (MIP) was prepared by non-covalent molecular imprinting with either (+) or (-)-Methylephedrine ((R*,S*)-2-(methylamino)-1phenylpropan-1-ol) as the template. Methacrylic acid and ethylene glycol di-methacrylate w...
متن کاملEffect of Template on Chiral Separation of Phenylalanine using Molecularly Imprinted Membrane in Aqueous Medium
L-Phenylalanine (L-Phe) and D-Phenylalanine (D-Phe) imprinted poly [(acrylonitrile)-co-(acrylic acid)] membranes were prepared by wet phase inversion method for chiral separation. The chiral separation ability of molecularly imprinted copolymer membranes towards the underivatized D,L-Phe aqueous mixture was evaluated by ultrafiltration experiment. The novel membranes show continuous permselecti...
متن کاملChiral separation of binaphthol enantiomers on molecularly imprinted polymer monolith by capillary electrochromatography.
A novel enantioseparational monolithic stationary phase for binaphthol based on a molecular imprinting method was introduced and evaluated in capillary electrochromatography (CEC). The monolithic stationary was prepared by the in situ copolymerization of methacrylic acid and ethylene glycol dimethacrylate in a porogenic solvent (toluene or toluene-isooctane) in the presence of an imprinting mol...
متن کاملSeparation of Racemic Mixtures of Amino Acids Using Chiral Eluents
A commercially available non-chiral RP-C8 chromatographic column is used with an aqueous chiral mobile phase containing N,N-dimethyl-L-phenylalanine and copper in a ratio 20 : 1 for the enantiomeric resolution of the following amino acids: DL-valine (Val), DL-methionine (Met), DL-leucine (Leu), DL-phenylalanine (Phe) and DL-tyrosine (Tyr). The influence of organic modifier, temperature and flow...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Ion Exchange
سال: 2003
ISSN: 1884-3360,0915-860X
DOI: 10.5182/jaie.14.supplement_329